Full List of Publications
Patents
Automated Detection of Breast Cancer Lesions in Tissue
R. Bhargava, F.N. Pounder, R.K. Reddy
U.S. Patent Application No. 13/222,623
Filed on August 31, 2011.
Apparatus for controlling the propagation and transmission of light in flexible
waveguides
G.J. Tearney, R.K. Reddy
Filed in April 2014.
Optical imaging device powered by light
G.J. Tearney, R.K. Reddy
Filed in April 2015.
Actively controlled optical imaging device
G.J. Tearney, R.K. Reddy, M.J. Gora, K.K. Chu, M. Beatty
Filed in September 2015.
Systems and methods for an actively controlled optical imaging device
G.J. Tearney, R.K. Reddy, M.J. Gora, K.K. Chu, M. Beatty, J. Dong, E. Beaulieu-Ouellet
Filed in 2018
Peer Reviewed Papers
Accurate histopathology from low signal-to-noise ratio spectroscopic imaging data
R.K. Reddy, R. Bhargava
Analyst, 135 , 2818-2825, 2010
[Paper]
Characterization of Tumor Progression in Engineered Tissue using Infrared Spectroscopic
Imaging
R. Kong, R.K. Reddy, R. Bhargava
Analyst, 135(7), 1569-1578, 2010
We made the cover of Analyst!
[Paper]
Dark Field Raman Microscopy
M.V. Schulmerich, R.K. Reddy, A.K. Kodali, L.J. Elgass, K. Tangella and R. Bhargava,
Anal. Chem., 82(14), 6273-6280, 2010
[Paper]
Label-free Biomedical Imaging with Mid- Infrared Spectroscopy
M.J. Walsh, R.K. Reddy, R. Bhargava,
IEEE Journal of Selected Topics in Quantum Electronics focusing on Biophotonics 2,
18(4), 1502-1513, 2012
[Paper]
Analysis of Variance components in Spectroscopic Imaging data of Tissue Microarray
J.T. Kwak, R.K. Reddy, S. Sinha, R. Bhargava
Anal. Chem., 84(12), 1063-1069, 2012
[Paper]
Discrete frequency infrared microspectroscopy and imaging with a tunable quantum cascade
laser
M.R. Kole, R.K. Reddy, M.V. Schulmerich, M.K. Gelber, R. Bhargava
Anal. Chem., 84(23), 10366-10372, 2012
[Paper]
High-definition Infrared Spectroscopic Imaging
R.K. Reddy, M.J. Walsh, M.V. Schulmerich, P. S. Carney, R. Bhargava
Appl. Spectrosc., 67(1), 93-105, 2013
William F. Meggers award winning paper!
[Paper]
Compositional prior information in computed infrared spectroscopic imaging
B.Deutsch, R.K. Reddy, D. Mayerich, R. Bhargava, P. S. Carney
Journal of the Optical Society of America A, 32(6) 1126 – 1131, 2015
[Paper]
Development of a practical spatial-spectral analysis
protocol for breast histopathology using Fourier transform infrared
spectroscopic imaging
F.N. Pounder, R.K. Reddy, R. Bhargava
Faraday discussions , 187, 43-68, 2016
[Paper]
uOCT imaging using depth of focus extension by self-imaging wavefront division in a common-path fiber optic probe
Biwei Yin, Kengyeh K. Chu, Chia-Pin Liang, Kanwarpal Singh, R.K. Reddy, and Guillermo J. Tearney
Optics express, 24(5), 5555-5564, 2016
[Paper]
Optimizing the Design of FT-IR Spectroscopic Imaging Instruments to Obtain Increased Spatial
Resolution of Chemical Species
R. Reddy, D. Mayerich, M. Walsh, M. Schulmerich, P. S. Carney, R. Bhargava,
International Symposium of Biomedical Imaging (ISBI), Barcelona, Spain, 2012
[Paper]
Rigorous Electromagnetic Model of Fourier Transform Infrared (FT-IR) Spectroscopic Imaging
Applied to Automated Histology of Prostate Tissue Specimens
R. Reddy, D. Mayerich, M. Walsh, P. S. Carney, R. Bhargava
International Conference on Optics, Lasers and Spectroscopy (ICOLS), Madrid, Spain,
2012.
[Paper]
Modeling Fourier Transform Infrared Spectroscopic Imaging of Prostate and Breast Cancer
Tissue Specimens
R.K. Reddy, B. Davis, P.S. Carney, R. Bhargava
International Symposium of Biomedical Imaging (ISBI), Chicago IL, 2011
[Paper]
Towards Better than Human Capability in Diagnosing Prostate Cancer Using Infrared
Spectroscopic Imaging Award winning paper!
X. Llora, R. Reddy, B. Matesic, R. Bhargava
Genetic and Evolutionary Computation Conference (GECCO), London UK, 2007
[Paper]
Book Chapters
Chemometric methods for biomedical Raman spectroscopy and imaging
R.K. Reddy and R. Bhargava
Book: Emerging Raman Applications and Techniques in Biomedical and Pharmaceutical
Fields
by M.D. Morris, P.Matousek, Springer-Verlag, Berlin Heidelberg, 2010
[Book]
Fourier transform infrared spectroscopic imaging: An emerging label-free approach for
molecular imaging
K. Yeh, R.K. Reddy and R. Bhargava
Book: Emerging Imaging Technologies in Medicine
by M. Anastasio, P.J. La Riviere, Taylor & Francis, Philadelphia, USA, 2012
[Book]
Ph.D. Thesis
Mid-Infrared Spectroscopic Imaging and Tomography
R.K. Reddy
Advisor: Dr.Rohit Bhargava
University of Illinois at Urbana Champaign, 2013.
Invited Talks
Design of high resolution FT-IR spectroscopic imaging instruments for improved breast cancer detection
R.K. Reddy, D. Mayerich, M.J. Walsh, P.S.Carney, R.Bhargava
SPIE Photonics West, San Fransisco, CA, Feb. 10th, 2015
Building mid-infrared spectroscopic imaging instruments for improved breast cancer detection
R.K. Reddy
Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Feb. 3rd, 2015
High Resolution FT-IR Imaging for Improvd Breast Cancer Detection
R.K. Reddy, D. Mayerich, M.J. Walsh, P.S.Carney, R.Bhargava
Science Exchange (SciX) conference organized by Federation of Analytical Chemistry
and Spectroscopy Societies (FACSS), Reno, NV, Oct. 1st, 2014
Seeing the unseen in human tissue
R.K. Reddy, K.K. Chu, T.N.Ford, K. Singh, R.W. Carruth, D. Hyun, H. Ma, D. Mojahed, C.
Unglert, G.J. Tearney,
Science Exchange (SciX) conference organized by Federation of Analytical Chemistry
and Spectroscopy Societies (FACSS), Reno, NV, Oct. 1st, 2014
Mid-infrared Spectroscopic Imaging and Tomography
R.K. Reddy, P.S.Carney, R.Bhargava
Massachusetts General Hospital, Harvard Medical School, July 9th, 2013
Instrumentation for Infrared Spectroscopic Imaging
R.K. Reddy, R.Bhargava
Lam Research, Fremont, California, October 23rd, 2012
Vibrational Spectroscopy
R.K. Reddy, Thomas van Dijk, R.Bhargava
Roger Adams Laboratory, University of Illinois at Urbana Champaign, Jan 31st, 2012
Fourier Transform Infrared (FT-IR) Spectroscopic Imaging of Human Tissue Specimens
R.K. Reddy, D. Mayerich, M.J. Walsh, M.V. Schulmerich, P.S.Carney, R.Bhargava
Beckman Graduate Seminar, Beckman Institute for Advanced Science and Technology,
Urbana IL, Nov 2, 2010
Conference Presentations
Tethered Capsule Endomicroscopy for Barretts Esophagus Screening
R.K. Reddy, M.J. Gora, R. Carruth, T.N. Ford, J. Dong, G.J. Tearney,
Science Exchange (SciX) conference organized by Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), Providence, RI, Oct. 1st, 2015
Functional micron-resolution imaging with micro-optical coherence tomography
R.K. Reddy, K.K. Chu, T.N.Ford, K. Singh, R.W. Carruth, D. Hyun, H. Ma, D. Mojahed, C. Unglert, G.J. Tearney
Science Exchange (SciX) conference organized by Federation of Analytical Chemistry and Spectroscopy Societies (FACSS) , Reno,
NV, Oct. 2nd, 2014
Improved Breast Cancer Detetion from High-Resolution Fourier Transform Infrared (FTIR)
Spectroscopic Imaging
R.K. Reddy, D. Mayerich, M.J. Walsh, M.V. Schulmerich, R. Bhargava
Science Exchange (SciX) conference organized by Federation of Analytical Chemistry and Spectroscopy Societies (FACSS) ,
Milwakee, WI, Oct. 3rd, 2013
Classification of Prostate and Breast Tissue Data from High-Resolution Fourier Transform
Infrared (FTIR) Spectroscopic Imaging
R.K. Reddy, D. Mayerich, M.J. Walsh, M.V. Schulmerich, R. Bhargava,
Science Exchange (SciX) conference organized by Federation of Analytical Chemistry and Spectroscopy Societies (FACSS) , Kansas
City, MO, Oct. 1st, 2012
High resolution FT-IR spectroscopic imaging instruments for cancer detection
R.K. Reddy, M.J. Walsh, M. Schulmerich, P.S. Carney, R. Bhargava
(Poster) Univ. of Illinois at Urbana Champaign Community at Illinois Symposium, Chicago, April 5th, 2012
Rigorous Electromagnetic Model of Fourier Transform Infrared (FT-IR) Spectroscopic Imaging
Applied to Automated Histology of Prostate Tissue Specimens
R.K. Reddy, D. Mayerich, M. Walsh, P. S. Carney, R. Bhargava
International Conference on Optics, Lasers and Spectroscopy (ICOLS), Madrid, Spain, March 28th, 2012
Design of high resolution FT-IR spectroscopic imaging instruments for cancer detection
R.K. Reddy, M.J. Walsh, M. Schulmerich, P.S. Carney, R. Bhargava
(Poster) Univ. of Illinois at Chicago Cancer Center Research Forum, Chicago, March 6th, 2012
High Definition Fourier Transform Infrared (FT-IR) Spectroscopic Imaging
R. Reddy, D. Mayerich, M. Walsh, M. Schulmerich, P.S. Carney, R. Bhargava
Midwest ACS meeting, Oct. 19th, 2011
Overcoming Spectral Distortions in Fourier Transform Infrared (FT-IR) Spectroscopic
Imaging
R.K. Reddy, P.S. Carney, R. Bhargava,
Federation of Analytical Chemistry and Spectroscopy Societies (FACSS) , Reno, NV, Oct. 2nd, 2011
Theory of resolution and image quality in mid-IR imaging
R. Bhargava, T. van Dijk, R.K. Reddy, P.S. Carney
Federation of Analytical Chemistry and Spectroscopy Societies (FACSS) 2011, Reno, October 3rd, 2011.
High-Definition FT-IR Spectroscopic Imaging
R.K. Reddy, R. Bhargava
Federation of Analytical Chemistry and Spectroscopy Societies (FACSS) , Reno, NV, Oct. 4th, 2011
High Definition Fourier Transform Infrared (FT-IR) Spectroscopic Imaging (Award Winning Poster!)
R.K. Reddy, M.J. Walsh, M. Schulmerich, P.S. Carney, R. Bhargava
(Poster) Federation of Analytical Chemistry and Spectroscopy Societies (FACSS) 2011, Reno, NV, Oct. 4th, 2011
Fourier-Transform Infrared Spectroscopic Imaging for Histopathology
R.K. Reddy, R.Bhargava
(Poster) BioSensing and BioActuation Summer Institute 2011, National Taiwan University, Taiwan, July 22nd, 2011
Modeling Fourier transform infrared spectroscopic imaging of Prostate and breast cancer
tissue specimens
R.K. Reddy, B.J. Davis, P.S. Carney, R. Bhargava
IEEE International Symposium on Biomedical Imaging (ISBI), Chicago, March 30th, 2011
Enhanced Models for Fourier Transform Infrared (FT-IR) Spectroscopic Imaging of Human Tissue
Specimens (Award Winning Poster!)
R.K. Reddy, B.J. Davis, P.S. Carney, R. Bhargava
Federation of Analytical Chemistry and Spectroscopy Societies FACSS ), Rayleigh, NC, Oct. 4th, 2010
Modeling, Data Visualization and Histopathology using Fourier Transform Infrared (FT-IR)
Spectroscopic Imaging of Human Tissue Specimens (Award Winning Poster!)
R.K. Reddy, F.N. Pounder, R. Bhargava
(Poster), Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), Louisville, KY, Oct. 19th, 2009
Modeling, Data Visualization and Histopathology using Fourier Transform Infrared (FT-IR)
Spectroscopic Imaging of Human Tissue Specimens
R.K. Reddy, R. Bhargava
Biomedical Engineering Society Conference (BMES), Pittsburgh, PA, Oct. 8th, 2009
Fourier-Transform Infrared Spectroscopic Imaging
R.K. Reddy, R.Bhargava
(Poster) NanoBiophotonics Summer School 2009, Urbana IL, June 4th, 2009
Advances in Automated Histopathology using Fourier Transform Infrared (FT-IR) Spectroscopic
Imaging
R.K. Reddy, R. Bhargava
(Poster) Univ. of Michigan at Ann Arbor, Midwestern Biomedical Engineering Conference, April 3rd, 2009
Robustness of Tissue Classification using FT-IR Imaging
R.K. Reddy, R. Bhargava
Federation of Analytical Chemistry and Spectroscopy Societies (FACSS) , Reno, NV, Sept. 30th, 2008
Enhancing the tissue segmentation capability of fast infrared spectroscopic imaging via
chemometric methods,
R. Bhargava, F.N. Pounder, R.K. Reddy, X. Llora
Federation of Analytical Chemistry and Spectroscopy Societies (FACSS) , Reno, NV, Sept. 30th, 2008
Advances in Automated Histopathology using Fourier Transform Infrared (FT-IR) Spectroscopic
Imaging
R.K. Reddy, R. Bhargava
(Poster) Biomedical Engineering Society Conference (BMES), St.Louis, MO, Oct 3rd, 2008
Computational Methods for Enhancing Infrared Spectroscopic Imaging (Award Winning Poster!)
R. Reddy, R.Bhargava
Federation of Analytical Chemistry and Spectroscopy Societies (FACSS) , Memphis TN, Oct 14th, 2007
Masters Thesis
3D Warped Discrete Cosine Transform and its application in Image Compression
R.Reddy, K.M.M.Prabhu
Indian Institute of Technology Madras, Chennai, India, July 2006.
Other Publications
Denoising and deblurring of Fourier-trasform infrared spectroscopic imaging
T.H. Nguyen, R.K. Reddy, M. J. Walsh, M. Schulmerich, G. Popescu, M.N. Do, R. Bhargava
Society of Photo-Optical Instrumentation Engineers (SPIE) Photonics West, Paper No. 8296-20, 2012
Re-imagining FT-IR imaging and applications with new theory and instruments
R. Bhargava, P.S. Carney, R.K. Reddy
SciX, Kansas City, October 2012
Development of highly sensitive and specific vibrational spectroscopic imaging guided by new theory
R. Bhargava, A.K. Kodali, X. Llora, R.K. Reddy, M.J. Walsh, P.S. Carney
EAS 2011, Somerset, NJ, November 2011
Validating the cancer diagnosis potential of mid-infrared spectroscopic imaging
F.N. Pounder, R.K. Reddy, M. Walsh and R. Bhargava
Society of Photo-Optical Instrumentation Engineers (SPIE 2009) Photonics West, Paper No. 7186-14, 2009
Practical protocols for ultrafast histopathology by Fourier transform infrared imaging
F.N. Keith, R.K. Reddy, and R. Bhargava
Society of Photo-Optical Instrumentation Engineers (SPIE) Photonics West, Paper No. 6853A-5, 2008